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Global Health Snapshot - Neglected Tropical Diseases

Global Health Snapshot: Neglected Tropical Diseases


LeishmaniasisA spectrum of diseases caused by the protozoan parasites (Leishmania), transmitted by sand flies.

Symptoms: Four types of disease range in severity, from skin sores on exposed areas to lesions that can destroy mucous membranes. In severe form, parasites cause swelling of spleen and liver.

Treatment: Antimony-containing compounds; also used: amphotericin B and fluconazole

Prevention: Bednets

Location: Southeast Asia, Middle East and South America

Prevalence: 12 million people infected worldwide

Trending: 1 to 2 million new cases each year

Fact: Drug-resistant Leishmania strains have been identified; need for new therapies is growing.

Devastating Loss: “As a student, I was struck by the amount of tissue destruction this parasite can cause. Skin breakdown [sometimes] can result in permanent disfigurement.”

Jay Bream focuses on the role of cytokines (soluble proteins) in disease susceptibility.


This forum is closed
  • Phyllis Sommer

    Chicago,Illinois 05/13/2011 11:21:40 AM

    Remember Chlamydia T. is a sexually transmitted disease and any prevention & teaching needs to include that fact. Condoms are number one prevention strategy. If people are warned about infertility as result of Chlamydia,they may be more amenable to condom use since fertility is highly valued in those countries.

  • Dr. B N Patnaik

    India 01/24/2012 02:23:35 AM

    I would like to know more about your C.trachomatis trail........I am preparing documents for clinical trailof Oral HPV vaccine in India .

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